Obesity is a multifaceted medical condition influenced by genetic, environmental, behavioral, and societal factors, marked by excessive body fat accumulation that poses significant risks to cardiometabolic health. It is a key contributor to a range of chronic conditions, including cardiovascular diseases, diabetes, and disorders affecting the liver, kidneys and joints. Advances in genomics and metabolomics have illuminated the significant genetic predisposition to obesity, highlighting that for many, weight regulation challenges extend beyond mere caloric intake and physical activity.
The foundation of weight management and prevention of chronic diseases is lifestyle, including a healthful diet, regular physical activity, quality sleep and stress reduction. For patients who have optimized these lifestyle factors through comprehensive programs including meeting with dietitians, yet continue to struggle with weight loss or maintenance, pharmacotherapy may offer a viable adjunct, with evidence demonstrating its potential benefits on cardiovascular health, diabetes prevention, and overall organ function.
Our integrative approach emphasizes a thorough cardiovascular risk assessment and the deployment of personalized interventions designed to enhance metabolic function and cardiovascular well-being. By adopting a holistic and nuanced perspective, we aim to empower patients with sustainable strategies to navigate their weight management journey while addressing the broader implications on their overall health.
